What Is Tris Promethazine-Codeine Syrup?
Tris Promethazine cough syrup. Tris Pharma manufactures a prescription cough syrup containing:
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Codeine phosphate (6.25mg/5mL) – Opioid cough suppressant
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Promethazine HCl (6.25mg/5mL) – Antihistamine for nausea/sedation
Key Facts
✔ Medical Use: Short-term severe cough relief
✔ DEA Schedule: Schedule V (U.S.) – Lower abuse potential than stronger opioids
✔ Street Names: “Tris,” “Purple Drank,” “Lean”
✔ Manufacturer: Tris Pharma (FDA-approved)
⚠️ Warning:
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Highly addictive (codeine is an opioid)
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Illegal without prescription (federal offense)
Tris Ingredients & Dosage
Active Ingredients (Per 5mL)
| Ingredient | Purpose | Amount |
|---|---|---|
| Codeine phosphate | Cough suppression | 6.25mg |
| Promethazine HCl | Anti-nausea/sedation | 6.25mg |
How It Works
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Codeine binds to brain receptors, reducing cough reflexes.
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Promethazine enhances sedation and relieves nausea.
🚨 Dangerous Interactions:
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Alcohol → Respiratory failure
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Benzodiazepines (Xanax, Valium) → Fatal overdose risk

Is Tris Syrup Still Available in 2024?
✅ Yes – but strictly prescription-only.
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Some rumors claim discontinuation, but Tris Pharma still produces it under tight regulations.
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Counterfeit risk is high – Fake versions may contain fentanyl or meth.
How to Spot Real Tris Pharma Syrup
✔ Holographic label with Tris Pharma branding
✔ Prescription documentation from licensed pharmacy
✔ Viscous purple liquid (not watery or discolored)
❌ Fake Tris Warning Signs:
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Misspelled labels (“Triss,” “Tris Pharma Inc.”)
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Sold on social media/telegram
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No National Drug Code (NDC) on packaging
Tris vs. Other Codeine Syrups (2024 Comparison)
| Brand | Codeine per 5mL | Promethazine per 5mL | Status |
|---|---|---|---|
| Tris Pharma | 6.25mg | 6.25mg | Available (Rx-only) |
| Wockhardt | 10mg | 6.25mg | Available (Rx-only) |
| Quagen | 6.25mg | 6.25mg | Available (Rx-only) |
| Actavis | 10mg | 6.25mg | Discontinued |
Key Difference: Tris has equal codeine/promethazine ratios (unlike stronger Wockhardt). Tris Promethazine cough syrup
Dangers of Tris Syrup Misuse
Short-Term Risks
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Extreme drowsiness 😴
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Slowed breathing (respiratory depression)
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Constipation 🤢
Long-Term Risks
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Opioid addiction (withdrawal symptoms include anxiety, muscle pain)
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Liver damage (from acetaminophen in some formulations)
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Overdose death (when mixed with alcohol/benzos)
💀 Overdose Symptoms:
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Pinpoint pupils 👁️
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Unresponsiveness 🛑
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Blue lips/fingertips 🔵
What to Do:
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Call 911 immediately
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Administer naloxone (Narcan) if available
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Do NOT let the person “sleep it off”
Legal Status of Tris Promethazine-Codeine
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U.S. Federal Law: Schedule V – Prescription required
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Strictest States: Texas, Florida (tracked databases)
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International:
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Banned in UAE, Japan
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Controlled in UK/Canada
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🌍 Illegal to Import: Customs seizures can lead to felony charges.
Safer Alternatives to Tris Syrup
Medical Cough Treatments
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Benzonatate (Tessalon Perles) – Non-opioid
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Dextromethorphan (Delsym) – OTC option
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Honey/menthol lozenges – For mild coughs
Harm Reduction (If Prescribed)
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Never mix with alcohol/sedatives
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Use naloxone (Narcan) if available
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Follow dosage exactly – No “double-dosing”
Tris Pharma Syrup FAQs
❓ Is Tris stronger than Quagen?
No – Both contain 6.25mg codeine/5mL.
❓ Can you buy Tris online legally?
❌ No – Only at pharmacies with valid prescription.
❓ What’s the street price for Tris?
⚠️ We don’t promote illegal activity – Prices vary due to counterfeit risks.
❓ How long does Tris stay in your system?
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Urine: 2-4 days
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Blood: 24 hours
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Hair: Up to 90 days
Help for Codeine Addiction
If you or someone is struggling:
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SAMHSA Hotline: 1-800-662-HELP (4357)
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Medically supervised detox (required for opioid withdrawal)
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MAT options: Buprenorphine/naloxone therapy














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