Anastrozole (Anazone) 1mg Tablets
A Potent, Highly Selective Aromatase Inhibitor
Anastrozole 1mg Tablets is a potent and highly selective non-steroidal aromatase inhibitor that plays a critical role in estrogen biosynthesis.
By inhibiting the aromatase enzyme, anastrozole effectively suppresses the conversion of androgens (primarily androstenedione and testosterone) to estrogens in peripheral tissues and within cancer tissue itself.
This mechanism significantly lowers serum estradiol concentrations without affecting the formation of adrenal corticosteroids or aldosterone.
Mechanism of Action: Aromatase Inhibition Anastrozole 1mg Tablets
Anastrozole’s primary mechanism of action involves the potent inhibition of the aromatase enzyme:
| Parameter | Details |
|---|---|
| IC50 (Human Placental Aromatase) | 15 nM |
| Mechanism | Inhibits the cytochrome P450 enzyme aromatase, blocking the conversion of androgens to estrogens |
Key Research Applications
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Hormone-Sensitive Cancer Research: Anastrozole is widely studied in the context of hormone receptor-positive breast cancer research due to its ability to reduce estrogen levels and thereby slow or stop the growth of estrogen-dependent cancer cells. Anastrozole 1mg Tablets
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Endocrinology & Hormone Modulation Studies: Researchers utilize anastrozole to investigate estrogen’s role in various physiological and pathological processes, making it a valuable tool in endocrinology studies.
Product Specifications
| Parameter | Details |
|---|---|
| Strength | 1 mg per tablet |
| Dosage Form | Film-coated tablet |
| Chemical Formula | C₁₇H₁₉N₅ |
| Molecular Weight | 293.37 g/mol |
| CAS Number | 120511-73-1 |
| Storage | Store at room temperature (below 25°C), protected from light and moisture |
Quality and Product Information
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Brand Reference: Anazone (generic anastrozole) is a film-coated tablet containing 1mg of the active ingredient anastrozole.




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